Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery 		0.200 Biomarker RGD The combination of 31409163

2020
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0002103
Disease: Atopic rhinitis
Atopic rhinitis 		0.200 Therapeutic RGD [Acupoint application of herbal paste relieves symptoms and naso-mucosal inflammatory response by down-regulating serum TGF-β1 in allergic rhinitis rats]. 31368266

2019
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental 		0.500 ModifyingMutation RGD Paclitaxel alleviates liver fibrosis induced by bile duct ligation in rats: Role of TGF-β1, IL-10 and c-Myc. 30243650

2018
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental 		0.500 Therapeutic RGD Heat shock protein 47 as indispensible participant in liver fibrosis: Possible protective effect of lactoferrin. 30092114

2018
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0521607
Disease: Peritoneal Fibrosis
Peritoneal Fibrosis 		0.600 Therapeutic RGD Abatacept as a therapeutic option in the treatment of encapsulated peritoneal sclerosis: an experimental rat model. 28190234

2017
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.600 Biomarker RGD Simvastatin ameliorates ventricular remodeling via the TGF‑β1 signaling pathway in rats following myocardial infarction. 27121011

2016
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C1397307
Disease: Cardiac fibrosis
Cardiac fibrosis 		0.300 Biomarker RGD Velvet antler peptide prevents pressure overload-induced cardiac fibrosis via transforming growth factor (TGF)-β1 pathway inhibition. 27108788

2016
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0242350
Disease: Erectile dysfunction
Erectile dysfunction 		0.210 Biomarker RGD Effects of Omega-3 Fatty Acids on Erectile Dysfunction in a Rat Model of Atherosclerosis-induced Chronic Pelvic Ischemia. 27051243

2016
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0016059
Disease: Fibrosis
Fibrosis 		0.600 Biomarker RGD Customized platelet-rich plasma with transforming growth factor β1 neutralization antibody to reduce fibrosis in skeletal muscle. 26923362

2016
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.700 Therapeutic RGD The results showed that BLM resulted in severe PF and diffuse lung inflammation, together with significant elevation of inflammatory factors and a marked increase in expression of angiotensin II (ANG II) and transforming growth factor-beta 1 (TGF-β1). 26822530

2016
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0027796
Disease: Neuralgia
Neuralgia 		0.200 Therapeutic RGD Flexibilide obtained from cultured soft coral has anti-neuroinflammatory and analgesic effects through the upregulation of spinal transforming growth factor-β1 in neuropathic rats. 24979268

2014
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0156257
Disease: Calculus of kidney and ureter
Calculus of kidney and ureter 		0.200 Therapeutic RGD Astaxanthin modulates osteopontin and transforming growth factor β1 expression levels in a rat model of nephrolithiasis: a comparison with citrate administration. 24712822

2014
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 Biomarker RGD The impact of 1,25-dihydroxyvitamin D3 on the expression of connective tissue growth factor and transforming growth factor-β1 in the myocardium of rats with diabetes. 24613393

2014
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.600 Therapeutic RGD Antioxidant and pro-oxidant effects of oil palm (Elaeis guineensis) leaves extract in experimental diabetic nephropathy: a duration-dependent outcome. 24074026

2013
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0041972
Disease: Urethral Obstruction
Urethral Obstruction 		0.200 Therapeutic RGD [Effect of coicis semen oil on renal interstitial fibrosis in rats with unilateral urethral obstruction]. 24066596

2013
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0033687
Disease: Proteinuria
Proteinuria 		0.500 Biomarker RGD Heterozygous knockout of transforming growth factor-β1 protects Dahl S rats against high salt-induced renal injury. 23249995

2013
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C1969372
Disease: Tubulointerstitial fibrosis
Tubulointerstitial fibrosis 		0.300 Biomarker RGD Heterozygous knockout of transforming growth factor-β1 protects Dahl S rats against high salt-induced renal injury. 23249995

2013
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0027055
Disease: Myocardial Reperfusion Injury
Myocardial Reperfusion Injury 		0.200 Therapeutic RGD Treatment with cardiotonic pills(®) after ischemia-reperfusion ameliorates myocardial fibrosis in rats. 22913380

2013
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.600 Biomarker RGD Early administration of propofol protects against endotoxin-induced acute lung injury in rats by inhibiting the TGF-beta1-Smad2 dependent pathway. 19941153

2010
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.600 Biomarker RGD Pyrrolidine dithiocarbamate attenuates paraquat-induced lung injury in rats. 19639047

2009
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0019284
Disease: Diaphragmatic Hernia
Diaphragmatic Hernia 		0.500 Biomarker RGD Effect of prenatal tetrandrine administration on transforming growth factor-beta1 level in the lung of nitrofen-induced congenital diaphragmatic hernia rat model. 19635314

2009
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.700 Biomarker RGD Silencing CD36 gene expression results in the inhibition of latent-TGF-beta1 activation and suppression of silica-induced lung fibrosis in the rat. 19439069

2009
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0020473
Disease: Hyperlipidemia
Hyperlipidemia 		0.200 Biomarker RGD Hyperlipidemia induced by high fat diet ingestion leads to renal injury in diabetic rats through activating TGF-beta1 /Smad signaling pathway. 19001732

2008
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0020476
Disease: Hyperlipoproteinemias
Hyperlipoproteinemias 		0.200 Biomarker RGD [Hyperlipidemia induced by high fat diet ingestion activates TGF-beta/Smad signaling pathway in the kidney of diabetic rats]. 19001732

2008
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0242350
Disease: Erectile dysfunction
Erectile dysfunction 		0.210 Biomarker RGD Role of increased penile expression of transforming growth factor-beta1 and activation of the Smad signaling pathway in erectile dysfunction in streptozotocin-induced diabetic rats. 18778311

2008